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Small GTPases in disease / edited by William E. Balch, Channing J. Der and Alan Hall
(Methods in enzymology. ISSN:00766879 ; v. 438)

出版者 Amsterdam, Netherlands ; Boston, MA : Elsevier Academic Press
出版年 2008
大きさ 1 online resource (xlviii, 463 pages, [14] pages of color plates) : illustrations
書誌ID MC00009198

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eBook オンライン資料

MC000048207
Elsevier ScienceDirect Books Complete 9780080877600
eBook オンライン資料

MC000065729
Elsevier ScienceDirect Books Complete 0080570070

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一般注記 Includes bibliographical references and index.
Print version record.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences. This volume is the first of two planned volumes on the topic of small GTPases and their role in disease.
1. Rab1b Silencing Using Small Interfering RNA for Analysis of Disease-Specific Function / Darren M. Hutt, William E. Balch -- 2. Rab8-Optineurin-Myosin VI: Analysis of Interactions and Functions in the Secretory Pathway / Margarita V. Chibalina, Rhys C. Roberts, Susan D. Arden, John Kendrick-Jones, Folma Buss -- 3. Characterization of Rab27a and JFC1 as Constituents of the Secretory Machinery of Prostate-Specific Antigen in Prostate Carcinoma Cells / Sergio D. Catz -- 4. In Vitro Assays to Characterize Inhibitors of the Activation of Small G Proteins by Their Guanine Nucleotide Exchange Factors / Jean-Christophe Zeeh, Bruno Antonny, Jacqueline Cherfils, Mahel Zeghouf -- 5. Analysis of Small GTPase Function in Trypanosomes / Mark C. Field, David Horn, Mark Carrington -- 6. Use of Dynasore, the Small Molecule Inhibitor of Dynamin, in the Regulation of Endocytosis / Tom Kirchhausen, Eric Macia, Henry E. Pelish -- 7. Identification and Verification of Sro7p as an Effector of the Sec4p Rab GTPase / Bianka L. Grosshans, Peter Novick -- 8. Characterization of Rab18, a Lipid Droplet-Associated Small GTPase / Sally Martin, Robert G. Parton -- 9. Analysis on the Emerging Role of Rab3 GTPase-Activating Protein in Warburg Micro and Martsolf Syndrome / Ayuko Sakane, Jun Miyoshi, Yoshimi Takai, Takuya Sasaki -- 10. Identification and Characterization of JRAB/MICAL-L2, a Junctional Rab13-Binding Protein / Noriyuki Nishimura, Takuya Sasaki -- 11. A SMAP Gene Family Encoding ARF GTPase-Activating Proteins and Its Implication in Membrane Trafficking / Kenji Tanabe, Shunsuke Kon, Nobuyuki Ichijo, Tomo Funaki, Waka Natsume, Toshio Watanabe, Masanobu Satake -- 12. In Vitro and In Vivo Analysis of Neurotrophin-3 Activation of Arf6 and Rac-1 / Pedro F. Esteban, Paola Caprari, Hye-Young Yoon, Paul A. Randazzo, Lino Tessarollo -- 13. Methods for Analysis of rab27a/munc13-4 in Secretory Lysosome Release in Hematopoietic Cells / Peter van der Sluijs, Maaike Neeft, Thijs van Vlijmen, Edo Elstak, Marnix Wieffer -- 14. Analysis and Expression of Rab38 in Oculocutaneous Lung Disease / Kazuhiro Osanai, Dennis R. Voelker -- 15. Analysis of Rab1 Function in Cardiomyocyte Growth / Catalin M. Filipeanu, Fuguo Zhou, Guangyu Wu -- 16. Regulation of the Trafficking and Function of G Protein-Coupled Receptors by Rab1 GTPase in Cardiomyocytes / Guangyu Wu -- 17. Regulation of Endosome Dynamics by Rab5 and Huntingtin-HAP40 Effector Complex in Physiological versus Pathological Conditions / Arun Pal, Fedor Severin, Sebastian Höpfner, Marino Zerial -- 18. Biochemical and Biophysical Analyses of Ras Modification by Ubiquitin / Sonia Terrillon, Dafna Bar-Sagi -- 19. Biochemical Characterization of Novel Germline BRAF and MEK Mutations in Cardio-Facio-Cutaneous Syndrome / Pablo Rodriguez-Viciana, Katherine A. Rauen -- 20. Biochemical and Biological Characterization of Tumor-Associated Mutations of p110[alpha] / Adam Denley, Marco Gymnopoulos, Jonathan R. Hart, Hao Jiang, Li Zhao, Peter K. Vogt -- 21. Characterization of the Rheb-mTOR Signaling Pathway in Mammalian Cells: Constitutive Active Mutants of Rheb and mTOR / Tatsuhiro Sato, Akiko Umetsu, Fuyuhiko Tamanoi -- 22. Characterization of RalB-Sec5-TBK1 Function in Human Oncogenesis / Yuchen Chien, Michael A. White -- 23. High-Throughput Lung Cancer Cell Line Screening for Genotype-Correlated Sensitivity to an EGFR Kinase Inhibitor / Ultan McDermott, Sreenath V. Sharma, Jeffrey Settleman -- 24. In Vitro Signaling by MAPK and NF[kappa]B Pathways Inhibited by Yersinia YopJ / Sohini Mukherjee, Kim Orth -- 25. Biological and Biochemical Characterization of Anthrax Lethal Factor, a Proteolytic Inhibitor of MEK Signaling Pathways / Jennifer L. Bromberg-White, Nicholas S. Duesbery -- 26. Genetic Analyses of the Role of RCE1 in RAS Membrane Association and Transformation / Martin O. Bergo, Annika M. Wahlstrom, Loren G. Fong, Stephen G. Young -- 27. Characterization of Kras-Mediated Pancreatic Tumorigenesis in Zebrafish / Jon M. Davison, Seung Woo Park, Jerry M. Rhee, Steven D. Leach -- 28. Genetic Modeling of Ras-Induced Human Rhabdomyosarcoma / Corinne M. Linardic, Christopher M. Counter
著者標目 Balch, William Edward 1949-
Der, Channing J
Hall, A
件 名 LCSH:Guanosine triphosphatase
LCSH:Enzymology
MESH:GTP Phosphohydrolase-Linked Elongation Factors
FREE:Enzymes
FREE:GTP Phosphohydrolases
FREE:Guanosine triphosphatase
FREE:SCIENCE -- Life Sciences -- Biochemistry  この組合せで検索
FREE:Enzymology
FREE:Guanosine triphosphatase
FREE:Electronic books
分 類 LCC:QP601
DC22:574.1925
資料種別 機械可読データファイル
巻冊次 ISBN:9780080877600
ISBN:0080877605
ISBN:0080570070
ISBN:9780080570075
XISBN:0123739683
XISBN:9780123739681