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Biothermodynamics / edited by Michael L. Johnson, Jo M. Holt and Gary K. Ackers
(Methods in enzymology ; v. 492)
出版者 | Amsterdam, Netherlands ; Boston, Mass : Elsevier/Academic Press |
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出版年 | ©2011 |
大きさ | 1 online resource (xliii, 323 pages, 8 unnumbered pages of plates) : illustrations (some color) |
書誌ID | MC00009724 |
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見る | 配架場所 | 巻 次 | 請求記号 | 資料番号 | 状 態 | 利用注記 | コメント | ISBN | 刷 年 | 自動書庫 | 予約/取寄 | 複写取寄 | 公費eDDS | 隣の本 |
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eBook | オンライン資料 |
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MC000048748 |
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Elsevier ScienceDirect Books Complete | 9780123860040 |
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一般注記 | Includes bibliographical references and indexes. A thermodynamic approach for the targeting of nucleic acid structures using their complementary single strands -- Thermodynamics of biological processes -- Protein stability in the presence of cosolutes -- Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell [alpha]-defensin cryptdin-4 -- Synergy of molecular dynamics and isothermal titration calorimetry in studies of allostery -- Using tryptophan fluorescence to measure the stability of membrane proteins folded in liposomes -- Non-B conformations of CAG repeats using 2-aminopurine -- Disulfide bond-mediated passenger domain stalling as a structural probe of autotransporter outer membrane secretion in vivo -- Strategies for the thermodynamic characterization of linked binding/local folding reactions within the native state application to the lid domain of adenylate kinase from Escherichia coli -- Fluorescence-detected sedimentation in dilute and highly concentrated solutions Print version record. The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. * Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules * Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research * Offers step-by-step lab instructions, including necessary equipment, from a global research community. Elsevier ScienceDirect Book Series Package - Methods in Enzymology (2000-ongoing) |
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著者標目 | Johnson, Michael L. 1947- Holt, Jo M Ackers, Gary K |
件 名 | LCSH:Thermodynamics LCSH:Protein binding LCSH:Protein-protein interactions LCSH:Ligands (Biochemistry) FREE:SCIENCE -- Life Sciences -- Biochemistry この組合せで検索 FREE:Ligands (Biochemistry) FREE:Protein binding FREE:Protein-protein interactions FREE:Thermodynamics MESH:Ligands MESH:Protein Array Analysis MESH:Carrier Proteins MESH:Thermodynamics FREE:Electronic books LCSH:Electronic books |
分 類 | LCC:QP601 DC22:574.1925 |
資料種別 | 機械可読データファイル |
巻冊次 | ISBN:9780123860040 ISBN:0123860040 ISBN:9780123860033 ISBN:0123860032 |