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Gene transfer vectors for clinical application / edited by Theodore Friedman
(Methods in enzymology ; v. 507)

出版者 Amsterdam, Netherlands ; Boston, Mass : Elsevier/Academic Press
出版年 2012
大きさ 1 online resource (l, 385 pages, 14 unnumbered pages of plates) : illustrations (some color)
書誌ID MC00009971

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eBook オンライン資料

MC000049002
Elsevier ScienceDirect Books Complete 9780123865106

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一般注記 This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design. Chapters provide an invaluable resource for academics, researchers and students alike. Iinternational board of authors. This volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design.
General principles of retrovirus vector design / Tammy Chang and Jiing-Kuan Yee -- Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID) / Alain Fischer, Salima Hacein-Bey-Abina, and Marina Cavazzana-Calvo -- Retrovirus and lentivirus vector design and methods of cell conditioning / Samantha Cooray, Steven J. Howe, and Adrian J. Thrasher -- Analysis of the clonal repertoire of gene-corrected cells in gene therapy / Anna Paruzynski [and others] -- Developing novel lentiviral vectors into clinical products / Anna Leath and Kenneth Cornetta -- Lentivirus vectors in [beta]-thalassemia / Emmanuel Payen [and others] -- Gene therapy for chronic granulomatous disease / Elizabeth M. Kang and Harry L. Malech -- Alternative splicing caused by lentiviral integration in the human genome / Arianna Moiani and Fulvio Mavilio -- Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2amice / Eugenio Montini and Daniela Cesana -- Lentiviral hematopoietic cell gene therapy for X-linked adrenoleukodystrophy / Nathalie Cartier [and others] -- Retroviral replicating vectors in cancer / Christopher R. Logg [and others] -- Adeno-associated virus vectorology, manufacturing, and clinical applications / Joshua C. Grieger and R. Jude Samulski -- Gene delivery to the retina : from mouse to man / Jean Bennett, Daniel C. Chung, and Albert Maguire -- Generation of hairpin-based RNAi vectors for biological and therapeutic application / Ryan L. Boudreau and Beverly L. Davidson -- Recombinant adeno-associated viral vector reference standards / Philippe Moullier and Richard O. Snyder -- NIH oversight of human gene transfer research involving retroviral, lentiviral, and adeno-associated virus vectors and the role of the NIH Recombinant DNA Advisory Committee / Marina O'Reilly [and others] -- Regulatory structures for gene therapy medicinal products in the European Union / Bettina Klug [and others]
Preface: The successful clinical use of viral vectors for human gene therapy. General principles of retrovirus vector design Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID) Retrovirus and lentivirus vector design and methods of cell conditioning Analysis of the clonal repertoire of gene corrected cells in gene therapy Developing novel lentiviral vectors into clinical products Lentivirus vectors in beta-thalassemia Gene Therapy for Chronic Granulomatous Disease Alternative splicing caused by lentiviral integration in the human genome Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a-/- mice Lentiviral Hematopoietic Cell Gene Therapy for X-linked Adrenoleukodystrophy Retroviral replicating vectors in cancer Adeno-associated virus vectorology, manufacturing and clinical applications Gene Delivery To The Retina: From Mouse To Man Generation of hairpin-based RNAi vectors for biological and therapeutic application Recombinant adeno-associated viral vector reference standards NIH oversight of human gene transfer research involving retroviral, lentiviral and adeno-associated virus vectors and the role of the NIH recombinant DNA advisory committee draft Regulatory structures for gene therapy medicinal products in the European Union
Includes bibliographical references and indexes.
Print version record.
Elsevier ScienceDirect Book Series Package - Methods in Enzymology (2000-ongoing)
著者標目 Friedmann, Theodore 1935-
件 名 LCSH:Gene therapy
LCSH:Genetic vectors
LCSH:Genetic transformation
MESH:Genetic Therapy
MESH:Genetic Vectors
MESH:Gene Transfer Techniques
FREE:PSYCHOLOGY -- Psychotherapy -- General  この組合せで検索
FREE:Gene therapy
FREE:Genetic transformation
FREE:Genetic vectors
FREE:Electronic books
LCSH:Electronic books
分 類 LCC:RB155.8
NLM:W1
NLM:QZ 52
DC23:615.8/95
資料種別 機械可読データファイル
巻冊次 ISBN:9780123865106
ISBN:0123865107
ISBN:9780123865090
ISBN:0123865093
XISBN:9780123865090
XISBN:0123865093