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Methods in protein design / edited by Amy E. Keating
(Methods in enzymology. ISSN:00766879 ; volume 523)

出版者 San Diego, Calif : Academic
出版年 2013
大きさ 1 online resource (xviii, 464 pages) : illustrations
書誌ID MC00010121

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eBook オンライン資料

MC000049155
Elsevier ScienceDirect Books Complete 9780123946294

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一般注記 Includes bibliographical references and indexes.
Computational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides
Print version record.
Elsevier ScienceDirect Book Series Package - Methods in Enzymology (2000-ongoing)
著者標目 Keating, Amy E
件 名 LCSH:Protein engineering
FREE:SCIENCE -- Biotechnology  この組合せで検索
FREE:Protein engineering
FREE:Electronic books
分 類 LCC:QP601
DC23:660.6/3
資料種別 機械可読データファイル
巻冊次 ISBN:9780123946294
ISBN:0123946298
XISBN:9780123942920
XISBN:0123942926